Neuroborreliosis - Is It Really Problem? Analysis of 1260 Cases with Lyme Disease

Could it be Lyme neuroborreliosis?

Lyme neuroborreliosis in cases of non-specific neurological symptoms.

BACKGROUND Analysis of cerebrospinal fluid is required in order to diagnose Lyme neuroborreliosis. We investigated the symptoms of patients in a highly endemic area who were referred for evaluation of possible Lyme neuroborreliosis, and explored whether cerebrospinal fluid analysis confirmed or ruled out the diagnosis. METHOD We reviewed the medical records of all patients who underwent lumba...

Lyme neuroborreliosis and dementia.

INTRODUCTION Descriptions of Lyme disease and dementia are rare. OBJECTIVE To describe patients with dementia and a positive "intrathecal anti-Borrelia antibody index" (AI), specific for neuroborreliosis. METHODS Among 1,594 patients seen for dementia, we prospectively identified and studied 20 patients (1.25%) with dementia and a positive AI. Patients underwent a battery of neuropsychologi...

Season is an unreliable predictor of Lyme neuroborreliosis.

INTRODUCTION Lyme neuroborreliosis (LNB) is a tick-borne infection of the nervous system caused by the spirochete Borrelia burgdorferi sensu lato. The primary symptoms are usually painful radiculitis, facial palsy and lymphocytic meningitis. The aim of this study was to provide data on the seasonal variation, anamnesis, symptoms, laboratory data and course of the disease in adults (≥ 16 years)....

Cerebrospinal Fluid in Lyme Neuroborreliosis

James J. Nocton,* Bradley J. Bloom,* Barbara J. Rutledge, David H. Persing, Eric L. Logigian, Christopher H. Schmid, and Allen C. Steere Divisions of Rheumatology/Immunology, Pediatric Rheumatology, and Clinical Care Research, New England Medical Center and Floating Hospital for Children, Tufts University School ofMedicine, and Division ofNeurology, Brigham and Women's Hospital, Harvard Medical...